Indiana University · PhD

Atharva Shah

AI × diffusion MRI

Mapping white-matter pathways, microstructure, and anisotropy — where machine learning meets the brain’s own wiring.

Research

Publications

Selected work in diffusion MRI, microstructure, and AI methods — curated from Google Scholar.

  • 2025 · Preprint

    FORCE: Forward modeling for complex microstructure estimation

    A.J. Shah, R.N. Henriques, A. Ramirez-Manzanares, P. Filipiak, S. Baete, et al.

    Forward-modeling framework for estimating complex white-matter microstructure from diffusion MRI, targeting anisotropy and restricted diffusion signatures.

  • 2026 · arXiv

    PRISM: Differentiable Analysis-by-Synthesis for Fixel Recovery in Diffusion MRI

    M. Abouagour, A. Shah, E. Garyfallidis

    Differentiable analysis-by-synthesis approach for recovering fixels from diffusion MRI measurements.

  • 2014 · 1909 citations · Frontiers in Neuroinformatics

    Dipy, a library for the analysis of diffusion MRI data

    E. Garyfallidis, M. Brett, B. Amirbekian, A. Rokem, S. Van Der Walt, et al.

    Open-source Python library for diffusion MRI analysis — reconstruction, tractography, and microstructure methods used across the neuroimaging community.

  • 2026 · medRxiv

    MOSAIC: Methylation-Oriented Site Analysis and Information Classifier for Robust Epigenomic Classification of Acute Leukemia

    A. Shah, D. Green, L. Wainmann, J. Karrs, P. Shah

    Epigenomic classifier for acute leukemia using methylation site analysis in clinical cohorts with variable tumor purity.

  • 2022 · 70 citations · Multimedia Tools and Applications

    A stock market trading framework based on deep learning architectures

    A. Shah, M. Gor, M. Sagar, M. Shah

    Deep learning architectures applied to stock market trading — published implementation exploring temporal signal modeling for financial decision systems.

  • 2023 · 11 citations · Green Technologies and Sustainability

    Hydraulic modelling of a catalytic converter for pollutant reduction in atmosphere

    A. Shah, M. Shah, M. Prajapati

    Hydraulic modelling study of catalytic converter performance for atmospheric pollutant reduction.

  • 2024 · Journal of Molecular Diagnostics

    Proof-of-Principle Solid Tumor Tissue of Origin Classifier Using Clinical Whole-Transcriptome Sequencing

    D. Bergman, A. Shah, D. Green, Z. Cieslak, R. Vyas, J. Karrs, et al.

    Clinical whole-transcriptome classifier for solid tumor tissue-of-origin at an academic cancer center.

Path

From scaffold to synthesis

The same arc that appears as chapters while you scroll the brain — written once, as a continuous essay.

Chapter 1 · Brainstem · corticospinal foot

Every intelligent system needs something solid to stand on.

Scaffold

2018–2022 · Nirma University · Mechanical Engineering

I trained on force, structure, and simulation — how physical systems hold under constraint. Modeling the real world became my ground floor: before I could read a brain, I had to learn how systems behave.

Chapter 2 · Internal capsule · ascending pathways

From that scaffold, signal needed a pathway upward.

Ascend

2022–2024 · Indiana University · Data Science

Statistics, machine learning, and deep learning taught me to carry patterns through uncertainty — vision, robotics, bioinformatics. Like ascending white-matter tracts, this chapter moved intent from structure into information.

Chapter 3 · Corpus callosum · hemispheric bridge

Then the path had to cross into another hemisphere: medicine.

Cross

2023 · Dartmouth · Machine Learning for Medicine

At Dartmouth I joined computation to clinical signal — AI for diagnostics. Callosal fibers link left and right; this was my bridge between engineering and care.

Chapter 4 · Arcuate fasciculus · association fibers

Crossing was not enough — I had to learn the language of the wires themselves.

Associate

2024– · GRG Lab · Diffusion MRI & DIPY

In the GRG lab I work on fiber reconstruction, microstructure, and open tooling in DIPY. Association pathways connect what we perceive to what we can say; this is how I learned to speak tractography — and share it.

Chapter 5 · Corona radiata · frontal synthesis

Now the pathways converge into purpose.

Synthesize

Ph.D. · Indiana University · Intelligent Systems Engineering

My PhD sits where artificial intelligence meets neuroimaging — diffusion MRI, anisotropy, and microstructure. Scaffold, ascent, crossing, and language meet here: methods that read the brain’s own wiring.

Contact

Let's build the next fiber of ideas

Open to research collaborations, open-source neuroimaging work, and conversations at the intersection of AI and diffusion MRI.

athshah@iu.edu

© 2026 Atharva Shah